APO RESEARCH · REPORT
Opioid-Induced Constipation
Although opioids are very effective for treating and managing pain, their use frequently results in opioid-induced constipation (OIC). Treatment options for OIC may be as simple as changing diet or as complicated as requiring several medicines and laxatives.
Product & engineering
Understand the product.
Although opioids are very effective for treating and managing pain, their use frequently results in opioid-induced constipation (OIC). Treatment options for OIC may be as simple as changing diet or as complicated as requiring several medicines and laxatives.
Selected research
Industry Growth & Trends
Global Opioid-Induced Constipation Industry Growth and Trends Forecast to 2032
Market perspective
Although opioids are very effective for treating and managing pain, their use frequently results in opioid-induced constipation (OIC). Treatment options for OIC may be as simple as changing diet or as complicated as requiring several medicines and laxatives.
Global Opioid-Induced Constipation key players include Sanofi, Bayer, Purdue Pharm, etc. Global top three manufacturers hold a share over 45%.
North America is the largest market, with a share about 55%, followed by Europe, and Asia-Pacific, both have a share about 35 percent.
Read the full market overview
In terms of product, Lubiprostone is the largest segment, with a share about 5%. And in terms of application, the largest application is Pharmacy, followed by Hospital, etc.
Report Scope
This report provides a structured, data-driven view of the global Opioid-Induced Constipation market, combining harmonized quantitative metrics with targeted qualitative insight to support business and growth strategy, market positioning, and capital allocation.
The Opioid-Induced Constipation market size, estimates, and forecasts are presented in terms of sales volume (K Units) and revenue (US$ million), with 2025 as the base year and historical and forecast data for 2021-2032. The report segments the global Opioid-Induced Constipation market by Type, Application, region/country, and company, provides regional market sizes at the segment level, profiles the competitive landscape and key players and their market ranks, and reviews technology trends and new product developments relevant to Opioid-Induced Constipation.
Key Companies & Market Share Insights
This section analyzes the strategies and performance of leading manufacturers in the global Opioid-Induced Constipation market, including portfolio focus, innovation and product development, mergers and acquisitions, collaborations, and geographic expansion used to sustain or enhance competitive positions. It also summarizes recent corporate developments and key financial indicators and provides global revenue, price, and sales volume data by manufacturer for 2020-2025, enabling benchmarking of scale, pricing, and market share and supporting assessment of market concentration through indicators such as CR5 and CR10.
Opioid-Induced Constipation Market by Company
Takeda Pharmaceuticals
Bayer
Sanofi
Mallinckrodt
Salix (Bausch Health)
AstraZeneca
Progenics Pharmaceuticals
Purdue Pharm
Nektar Therapeutics
Daiichi Sankyo
Prestige
GSK
Shionogi
Opioid-Induced Constipation Segment by Type
Methylnaltrexone Bromide
Lubiprostone
Naloxegol
Others
Opioid-Induced Constipation Segment by Application
Hospital
Pharmacy
Other
Opioid-Induced Constipation Segment by Region
North America
United States
Canada
Mexico
Europe
Germany
France
U.K.
Italy
Russia
Spain
Netherlands
Switzerland
Sweden
Poland
Asia-Pacific
China
Japan
South Korea
India
Australia
Taiwan
Southeast Asia
South America
Brazil
Argentina
Chile
Middle East & Africa
Egypt
South Africa
Israel
Türkiye
GCC Countries
Key Drivers & Barriers
High-impact rendering factors and drivers have been studied in this report to aid the readers to understand the general development. Moreover, the report includes restraints and challenges that may act as stumbling blocks on the way of the players. This will assist the users to be attentive and make informed decisions related to business. Specialists have also laid their focus on the upcoming business prospects.
Reasons to Buy This Report
1. This report will help the readers to understand the competition within the industries and strategies for the competitive environment to enhance the potential profit. The report also focuses on the competitive landscape of the global Opioid-Induced Constipation market, and introduces in detail the market share, industry ranking, competitor ecosystem, market performance, new product development, operation situation, expansion, and acquisition. etc. of the main players, which helps the readers to identify the main competitors and deeply understand the competition pattern of the market.
2. This report will help stakeholders to understand the global industry status and trends of Opioid-Induced Constipation and provides them with information on key market drivers, restraints, challenges, and opportunities.
3. This report will help stakeholders to understand competitors better and gain more insights to strengthen their position in their businesses. The competitive landscape section includes the market share and rank (in volume and value), competitor ecosystem, new product development, expansion, and acquisition.
4. This report stays updated with novel technology integration, features, and the latest developments in the market.
5. This report helps stakeholders to gain insights into which regions to target globally.
6. This report helps stakeholders to gain insights into the end-user perception concerning the adoption of Opioid-Induced Constipation.
7. This report helps stakeholders to identify some of the key players in the market and understand their valuable contribution.
Chapter Outline
Chapter 1: Introduces the study scope of this report, executive summary of market segments by type, market size segments for North America, Europe, Asia Pacific, South America, Middle East & Africa.
Chapter 2: Introduces the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.
Chapter 3: Detailed analysis of Opioid-Induced Constipation manufacturers competitive landscape, price, sales, revenue, market share and ranking, latest development plan, merger, and acquisition information, etc.
Chapter 4: Sales, revenue of Opioid-Induced Constipation in regional level. It provides a quantitative analysis of the market size and development potential of each region and introduces the future development prospects, and market space in the world.
Chapter 5: Introduces market segments by application, market size segment for North America, Europe, Asia Pacific, South America, Middle East & Africa.
Chapter 6: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product sales, revenue, price, gross margin, product introduction, recent development, etc.
Chapter 7, 8, 9, 10 and 11: North America, Europe, Asia Pacific, South America, Middle East & Africa, sales and revenue by country.
Chapter 12: Analysis of industrial chain, key raw materials, manufacturing cost, and market dynamics.
Chapter 13: Concluding Insights of the report.
More report detail
Tables and figures
Scope & coverage.
Types
- Methylnaltrexone Bromide
- Lubiprostone
- Naloxegol
- Others
Applications
- Hospital
- Pharmacy
- Other
Companies covered
- Takeda Pharmaceuticals
- Bayer
- Sanofi
- Mallinckrodt
- Salix (Bausch Health)
- AstraZeneca
- Progenics Pharmaceuticals
- Purdue Pharm
- Nektar Therapeutics
- Daiichi Sankyo
- Prestige
- GSK
- Shionogi
Inside the report.
1 Market Overview
- 1.1 Product Definition
- 1.2 Global Market Growth Prospects
- 1.2.1 Global Opioid-Induced Constipation Market Size Estimates and Forecasts (2021-2032)
- 1.2.2 Global Opioid-Induced Constipation Sales Estimates and Forecasts (2021-2032)
- 1.3 Opioid-Induced Constipation Market by Type
- 1.3.1 Methylnaltrexone Bromide
- 1.3.2 Lubiprostone
- 1.3.3 Naloxegol
- 1.3.4 Others
- 1.4 Global Opioid-Induced Constipation Market Size by Type
- 1.4.1 Global Opioid-Induced Constipation Market Size Overview by Type (2021-2032)
- 1.4.2 Global Opioid-Induced Constipation Historic Market Size Review by Type (2021-2026)
- 1.4.3 Global Opioid-Induced Constipation Forecasted Market Size by Type (2027-2032)
- 1.5 Key Regions Market Size by Type
- 1.5.1 North America Opioid-Induced Constipation Sales Breakdown by Type (2021-2026)
- 1.5.2 Europe Opioid-Induced Constipation Sales Breakdown by Type (2021-2026)
- 1.5.3 Asia-Pacific Opioid-Induced Constipation Sales Breakdown by Type (2021-2026)
- 1.5.4 South America Opioid-Induced Constipation Sales Breakdown by Type (2021-2026)
- 1.5.5 Middle East and Africa Opioid-Induced Constipation Sales Breakdown by Type (2021-2026)
2 Global Market Dynamics
- 2.1 Opioid-Induced Constipation Industry Trends
- 2.2 Opioid-Induced Constipation Industry Drivers
- 2.3 Opioid-Induced Constipation Industry Opportunities and Challenges
- 2.4 Opioid-Induced Constipation Industry Restraints
3 Market Competitive Landscape by Company
- 3.1 Global Top Players by Opioid-Induced Constipation Revenue (2021-2026)
- 3.2 Global Top Players by Opioid-Induced Constipation Sales (2021-2026)
- 3.3 Global Top Players by Opioid-Induced Constipation Price (2021-2026)
- 3.4 Global Opioid-Induced Constipation Industry Company Ranking, 2024 VS 2025 VS 2026
- 3.5 Global Opioid-Induced Constipation Major Company Production Sites & Headquarters
- 3.6 Global Opioid-Induced Constipation Company, Product Type & Application
- 3.7 Global Opioid-Induced Constipation Company Establishment Date
- 3.8 Market Competitive Analysis
- 3.8.1 Global Opioid-Induced Constipation Market CR5 and HHI
- 3.8.2 Global Top 5 and 10 Opioid-Induced Constipation Players Market Share by Revenue in 2025
- 3.8.3 2025 Opioid-Induced Constipation Tier 1, Tier 2, and Tier 3
4 Opioid-Induced Constipation Regional Status and Outlook
- 4.1 Global Opioid-Induced Constipation Market Size and CAGR by Region: 2021 VS 2025 VS 2032
- 4.2 Global Opioid-Induced Constipation Historic Market Size by Region
- 4.2.1 Global Opioid-Induced Constipation Sales in Volume by Region (2021-2026)
- 4.2.2 Global Opioid-Induced Constipation Sales in Value by Region (2021-2026)
- 4.2.3 Global Opioid-Induced Constipation Sales (Volume & Value), Price and Gross Margin (2021-2026)
- 4.3 Global Opioid-Induced Constipation Forecasted Market Size by Region
- 4.3.1 Global Opioid-Induced Constipation Sales in Volume by Region (2027-2032)
- 4.3.2 Global Opioid-Induced Constipation Sales in Value by Region (2027-2032)
- 4.3.3 Global Opioid-Induced Constipation Sales (Volume & Value), Price and Gross Margin (2027-2032)
5 Opioid-Induced Constipation by Application
- 5.1 Opioid-Induced Constipation Market by Application
- 5.1.1 Hospital
- 5.1.2 Pharmacy
- 5.1.3 Other
- 5.2 Global Opioid-Induced Constipation Market Size by Application
- 5.2.1 Global Opioid-Induced Constipation Market Size Overview by Application (2021-2032)
- 5.2.2 Global Opioid-Induced Constipation Historic Market Size Review by Application (2021-2026)
- 5.2.3 Global Opioid-Induced Constipation Forecasted Market Size by Application (2027-2032)
- 5.3 Key Regions Market Size by Application
- 5.3.1 North America Opioid-Induced Constipation Sales Breakdown by Application (2021-2026)
- 5.3.2 Europe Opioid-Induced Constipation Sales Breakdown by Application (2021-2026)
- 5.3.3 Asia-Pacific Opioid-Induced Constipation Sales Breakdown by Application (2021-2026)
- 5.3.4 South America Opioid-Induced Constipation Sales Breakdown by Application (2021-2026)
- 5.3.5 Middle East and Africa Opioid-Induced Constipation Sales Breakdown by Application (2021-2026)
6 Company Profiles
- 6.1 Takeda Pharmaceuticals
- 6.1.1 Takeda Pharmaceuticals Company Information
- 6.1.2 Takeda Pharmaceuticals Business Overview
- 6.1.3 Takeda Pharmaceuticals Opioid-Induced Constipation Sales, Revenue and Gross Margin (2021-2026)
- 6.1.4 Takeda Pharmaceuticals Opioid-Induced Constipation Product Portfolio
- 6.1.5 Takeda Pharmaceuticals Recent Developments
- 6.2 Bayer
- 6.2.1 Bayer Company Information
- 6.2.2 Bayer Business Overview
- 6.2.3 Bayer Opioid-Induced Constipation Sales, Revenue and Gross Margin (2021-2026)
- 6.2.4 Bayer Opioid-Induced Constipation Product Portfolio
- 6.2.5 Bayer Recent Developments
- 6.3 Sanofi
- 6.3.1 Sanofi Company Information
- 6.3.2 Sanofi Business Overview
- 6.3.3 Sanofi Opioid-Induced Constipation Sales, Revenue and Gross Margin (2021-2026)
- 6.3.4 Sanofi Opioid-Induced Constipation Product Portfolio
- 6.3.5 Sanofi Recent Developments
- 6.4 Mallinckrodt
- 6.4.1 Mallinckrodt Company Information
- 6.4.2 Mallinckrodt Business Overview
- 6.4.3 Mallinckrodt Opioid-Induced Constipation Sales, Revenue and Gross Margin (2021-2026)
- 6.4.4 Mallinckrodt Opioid-Induced Constipation Product Portfolio
- 6.4.5 Mallinckrodt Recent Developments
- 6.5 Salix (Bausch Health)
- 6.5.1 Salix (Bausch Health) Company Information
- 6.5.2 Salix (Bausch Health) Business Overview
- 6.5.3 Salix (Bausch Health) Opioid-Induced Constipation Sales, Revenue and Gross Margin (2021-2026)
- 6.5.4 Salix (Bausch Health) Opioid-Induced Constipation Product Portfolio
- 6.5.5 Salix (Bausch Health) Recent Developments
- 6.6 AstraZeneca
- 6.6.1 AstraZeneca Company Information
- 6.6.2 AstraZeneca Business Overview
- 6.6.3 AstraZeneca Opioid-Induced Constipation Sales, Revenue and Gross Margin (2021-2026)
- 6.6.4 AstraZeneca Opioid-Induced Constipation Product Portfolio
- 6.6.5 AstraZeneca Recent Developments
- 6.7 Progenics Pharmaceuticals
- 6.7.1 Progenics Pharmaceuticals Company Information
- 6.7.2 Progenics Pharmaceuticals Business Overview
- 6.7.3 Progenics Pharmaceuticals Opioid-Induced Constipation Sales, Revenue and Gross Margin (2021-2026)
- 6.7.4 Progenics Pharmaceuticals Opioid-Induced Constipation Product Portfolio
- 6.7.5 Progenics Pharmaceuticals Recent Developments
- 6.8 Purdue Pharm
- 6.8.1 Purdue Pharm Company Information
- 6.8.2 Purdue Pharm Business Overview
- 6.8.3 Purdue Pharm Opioid-Induced Constipation Sales, Revenue and Gross Margin (2021-2026)
- 6.8.4 Purdue Pharm Opioid-Induced Constipation Product Portfolio
- 6.8.5 Purdue Pharm Recent Developments
- 6.9 Nektar Therapeutics
- 6.9.1 Nektar Therapeutics Company Information
- 6.9.2 Nektar Therapeutics Business Overview
- 6.9.3 Nektar Therapeutics Opioid-Induced Constipation Sales, Revenue and Gross Margin (2021-2026)
- 6.9.4 Nektar Therapeutics Opioid-Induced Constipation Product Portfolio
- 6.9.5 Nektar Therapeutics Recent Developments
- 6.10 Daiichi Sankyo
- 6.10.1 Daiichi Sankyo Company Information
- 6.10.2 Daiichi Sankyo Business Overview
- 6.10.3 Daiichi Sankyo Opioid-Induced Constipation Sales, Revenue and Gross Margin (2021-2026)
- 6.10.4 Daiichi Sankyo Opioid-Induced Constipation Product Portfolio
- 6.10.5 Daiichi Sankyo Recent Developments
- 6.11 Prestige
- 6.11.1 Prestige Company Information
- 6.11.2 Prestige Business Overview
- 6.11.3 Prestige Opioid-Induced Constipation Sales, Revenue and Gross Margin (2021-2026)
- 6.11.4 Prestige Opioid-Induced Constipation Product Portfolio
- 6.11.5 Prestige Recent Developments
- 6.12 GSK
- 6.12.1 GSK Company Information
- 6.12.2 GSK Business Overview
- 6.12.3 GSK Opioid-Induced Constipation Sales, Revenue and Gross Margin (2021-2026)
- 6.12.4 GSK Opioid-Induced Constipation Product Portfolio
- 6.12.5 GSK Recent Developments
- 6.13 Shionogi
- 6.13.1 Shionogi Company Information
- 6.13.2 Shionogi Business Overview
- 6.13.3 Shionogi Opioid-Induced Constipation Sales, Revenue and Gross Margin (2021-2026)
- 6.13.4 Shionogi Opioid-Induced Constipation Product Portfolio
- 6.13.5 Shionogi Recent Developments
7 North America by Country
- 7.1 North America Opioid-Induced Constipation Sales by Country
- 7.1.1 North America Opioid-Induced Constipation Sales Growth Rate (CAGR) by Country: 2021 VS 2025 VS 2032
- 7.1.2 North America Opioid-Induced Constipation Sales by Country (2021-2026)
- 7.1.3 North America Opioid-Induced Constipation Sales Forecast by Country (2027-2032)
- 7.2 North America Opioid-Induced Constipation Market Size by Country
- 7.2.1 North America Opioid-Induced Constipation Market Size Growth Rate (CAGR) by Country: 2021 VS 2025 VS 2032
- 7.2.2 North America Opioid-Induced Constipation Market Size by Country (2021-2026)
- 7.2.3 North America Opioid-Induced Constipation Market Size Forecast by Country (2027-2032)
8 Europe by Country
- 8.1 Europe Opioid-Induced Constipation Sales by Country
- 8.1.1 Europe Opioid-Induced Constipation Sales Growth Rate (CAGR) by Country: 2021 VS 2025 VS 2032
- 8.1.2 Europe Opioid-Induced Constipation Sales by Country (2021-2026)
- 8.1.3 Europe Opioid-Induced Constipation Sales Forecast by Country (2027-2032)
- 8.2 Europe Opioid-Induced Constipation Market Size by Country
- 8.2.1 Europe Opioid-Induced Constipation Market Size Growth Rate (CAGR) by Country: 2021 VS 2025 VS 2032
- 8.2.2 Europe Opioid-Induced Constipation Market Size by Country (2021-2026)
- 8.2.3 Europe Opioid-Induced Constipation Market Size Forecast by Country (2027-2032)
9 Asia-Pacific by Country
- 9.1 Asia-Pacific Opioid-Induced Constipation Sales by Country
- 9.1.1 Asia-Pacific Opioid-Induced Constipation Sales Growth Rate (CAGR) by Country: 2021 VS 2025 VS 2032
- 9.1.2 Asia-Pacific Opioid-Induced Constipation Sales by Country (2021-2026)
- 9.1.3 Asia-Pacific Opioid-Induced Constipation Sales Forecast by Country (2027-2032)
- 9.2 Asia-Pacific Opioid-Induced Constipation Market Size by Country
- 9.2.1 Asia-Pacific Opioid-Induced Constipation Market Size Growth Rate (CAGR) by Country: 2021 VS 2025 VS 2032
- 9.2.2 Asia-Pacific Opioid-Induced Constipation Market Size by Country (2021-2026)
- 9.2.3 Asia-Pacific Opioid-Induced Constipation Market Size Forecast by Country (2027-2032)
10 South America by Country
- 10.1 South America Opioid-Induced Constipation Sales by Country
- 10.1.1 South America Opioid-Induced Constipation Sales Growth Rate (CAGR) by Country: 2021 VS 2025 VS 2032
- 10.1.2 South America Opioid-Induced Constipation Sales by Country (2021-2026)
- 10.1.3 South America Opioid-Induced Constipation Sales Forecast by Country (2027-2032)
- 10.2 South America Opioid-Induced Constipation Market Size by Country
- 10.2.1 South America Opioid-Induced Constipation Market Size Growth Rate (CAGR) by Country: 2021 VS 2025 VS 2032
- 10.2.2 South America Opioid-Induced Constipation Market Size by Country (2021-2026)
- 10.2.3 South America Opioid-Induced Constipation Market Size Forecast by Country (2027-2032)
11 Middle East and Africa by Country
- 11.1 Middle East and Africa Opioid-Induced Constipation Sales by Country
- 11.1.1 Middle East and Africa Opioid-Induced Constipation Sales Growth Rate (CAGR) by Country: 2021 VS 2025 VS 2032
- 11.1.2 Middle East and Africa Opioid-Induced Constipation Sales by Country (2021-2026)
- 11.1.3 Middle East and Africa Opioid-Induced Constipation Sales Forecast by Country (2027-2032)
- 11.2 Middle East and Africa Opioid-Induced Constipation Market Size by Country
- 11.2.1 Middle East and Africa Opioid-Induced Constipation Market Size Growth Rate (CAGR) by Country: 2021 VS 2025 VS 2032
- 11.2.2 Middle East and Africa Opioid-Induced Constipation Market Size by Country (2021-2026)
- 11.2.3 Middle East and Africa Opioid-Induced Constipation Market Size Forecast by Country (2027-2032)
12 Value Chain and Sales Channels Analysis
- 12.1 Opioid-Induced Constipation Value Chain Analysis
- 12.1.1 Opioid-Induced Constipation Key Raw Materials
- 12.1.2 Key Raw Materials Price
- 12.1.3 Raw Materials Key Suppliers
- 12.1.4 Manufacturing Cost Structure
- 12.1.5 Opioid-Induced Constipation Production Mode & Process
- 12.2 Opioid-Induced Constipation Sales Channels Analysis
- 12.2.1 Direct Comparison with Distribution Share
- 12.2.2 Opioid-Induced Constipation Distributors
- 12.2.3 Opioid-Induced Constipation Customers
13 Concluding Insights
14 Appendix
- 14.1 Reasons for Doing This Study
- 14.2 Research Methodology
- 14.3 Research Process
- 14.4 Authors List of This Report
- 14.5 Data Source
- 14.5.1 Secondary Sources
- 14.5.2 Primary Sources
- 14.6 Disclaimer
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