APO RESEARCH · REPORT
Human Prothrombin Complex
Prothrombin complex concentrate (PCC), also known as factor IX complex, is a medication made up of blood clotting factors II, IX, and X. Some versions also contain factor VII. It is used to treat and prevent bleeding in hemophilia B if pure factor IX is not available.
Product & engineering
Understand the product.
Prothrombin complex concentrate (PCC), also known as factor IX complex, is a medication made up of blood clotting factors II, IX, and X. Some versions also contain factor VII. It is used to treat and prevent bleeding in hemophilia B if pure factor IX is not available.
Selected research
Industry Research
Human Prothrombin Complex Industry Research Report 2026
Market perspective
Prothrombin complex concentrate (PCC), also known as factor IX complex, is a medication made up of blood clotting factors II, IX, and X. Some versions also contain factor VII. It is used to treat and prevent bleeding in hemophilia B if pure factor IX is not available.
Global Human Prothrombin Complex key players include Octapharma, Shire, CSL, etc. Global top three manufacturers hold a share over 75%.
North America is the largest market, with a share about 45%, followed by Europe, and Asia-Pacific, both have a share about 45 percent.
Read the full market overview
In terms of product, 500 IU/Vial is the largest segment, with a share over 50%. And in terms of application, the largest application is Hemophilia B, followed by Vitamin K Deficiency, etc.
Report Scope
This report quantifies the global Human Prothrombin Complex market in terms of revenue (US$ million) and, where applicable, sales volume (K Units), using 2025 as the base year and providing annual historical and forecast data for 2021–2032.
It standardizes definitions of Types and Applications, harmonizes vendor attribution, and presents comparable time series by company, Type, Application, and region/country, including indicative price bands (US$/K Units) and concentration ratios (CR5/CR10).
The outputs are intended to support strategy development, budgeting, and performance benchmarking for brand owners, manufacturers, retailers, channel partners, and investors; data are structured with consistent units and fields to facilitate integration into internal FP&A and BI systems.
Key Companies & Market Share Insights
This section profiles leading manufacturers, combining 2021–2025 results with a 2026–2032 outlook. It reports revenue, market share, price bands, product and application mix, regional and channel mix, and key developments (M&A, capacity additions, certifications). It also provides global revenue, average price, and—where applicable—sales volume by manufacturer, and calculates CR5/CR10 and rank changes to support comparative benchmarking.
Human Prothrombin Complex Market by Company
Takeda
CSL
Grifols
Octapharma
Hualan Biological
Meheco Xinxing Pharma
Human Prothrombin Complex Segment by Type
500 IU/Vial
600 IU/Vial
1000 IU/Vial
Others
Human Prothrombin Complex Segment by Application
Hemophilia B
Vitamin K Deficiency
Others
Human Prothrombin Complex Segment by Region
North America
United States
Canada
Mexico
Europe
Germany
France
U.K.
Italy
Russia
Spain
Netherlands
Switzerland
Sweden
Poland
Asia-Pacific
China
Japan
South Korea
India
Australia
Taiwan
Southeast Asia
South America
Brazil
Argentina
Chile
Middle East & Africa
Egypt
South Africa
Israel
Türkiye
GCC Countries
Key Drivers & Barriers
High-impact rendering factors and drivers have been studied in this report to aid the readers to understand the general development. Moreover, the report includes restraints and challenges that may act as stumbling blocks on the way of the players. This will assist the users to be attentive and make informed decisions related to business. Specialists have also laid their focus on the upcoming business prospects.
Reasons to Buy This Report
1. This report will help the readers to understand the competition within the industries and strategies for the competitive environment to enhance the potential profit. The report also focuses on the competitive landscape of the global Human Prothrombin Complex market, and introduces in detail the market share, industry ranking, competitor ecosystem, market performance, new product development, operation situation, expansion, and acquisition. etc. of the main players, which helps the readers to identify the main competitors and deeply understand the competition pattern of the market.
2. This report will help stakeholders to understand the global industry status and trends of Human Prothrombin Complex and provides them with information on key market drivers, restraints, challenges, and opportunities.
3. This report will help stakeholders to understand competitors better and gain more insights to strengthen their position in their businesses. The competitive landscape section includes the market share and rank (in volume and value), competitor ecosystem, new product development, expansion, and acquisition.
4. This report stays updated with novel technology integration, features, and the latest developments in the market
5. This report helps stakeholders to gain insights into which regions to target globally
6. This report helps stakeholders to gain insights into the end-user perception concerning the adoption of Human Prothrombin Complex.
7. This report helps stakeholders to identify some of the key players in the market and understand their valuable contribution.
Chapter Outline
Chapter 1: Research objectives, research methods, data sources, data cross-validation;
Chapter 2: Introduces the report scope of the report, executive summary of different market segments (by region, product type, application, etc.), including the market size of each market segment, future development potential, and so on. It offers a high-level view of the current state of the market and its likely evolution in the short to mid-term, and long term.
Chapter 3: Detailed analysis of Human Prothrombin Complex manufacturers competitive landscape, price, production and value market share, latest development plan, merger, and acquisition information, etc.
Chapter 4: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product production/output, value, price, gross margin, product introduction, recent development, etc.
Chapter 5: Production/output, value of Human Prothrombin Complex by region/country. It provides a quantitative analysis of the market size and development potential of each region in the next six years.
Chapter 6: Consumption of Human Prothrombin Complex in regional level and country level. It provides a quantitative analysis of the market size and development potential of each region and its main countries and introduces the market development, future development prospects, market space, and production of each country in the world.
Chapter 7: Provides the analysis of various market segments by type, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.
Chapter 8: Provides the analysis of various market segments by application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.
Chapter 9: Analysis of industrial chain, including the upstream and downstream of the industry.
Chapter 10: Introduces the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.
Chapter 11: The main points and conclusions of the report.
More report detail
Tables and figures
Scope & coverage.
Types
- 500 IU/Vial
- 600 IU/Vial
- 1000 IU/Vial
- Others
Applications
- Hemophilia B
- Vitamin K Deficiency
- Others
Companies covered
- Takeda
- CSL
- Grifols
- Octapharma
- Hualan Biological
- Meheco Xinxing Pharma
Inside the report.
1 Preface
- 1.1 Scope of Report
- 1.2 Reasons for Doing This Study
- 1.3 Research Methodology
- 1.4 Research Process
- 1.5 Data Source
- 1.5.1 Secondary Sources
- 1.5.2 Primary Sources
2 Market Overview
- 2.1 Product Definition
- 2.2 Global Market Growth Prospects
- 2.2.1 Global Human Prothrombin Complex Market Size (2021-2032)
- 2.2.2 Global Human Prothrombin Complex Sales (2021-2032)
- 2.2.3 Global Human Prothrombin Complex Market Average Price (2021-2032)
- 2.3 Human Prothrombin Complex by Type
- 2.3.1 Market Value Comparison by Type (2021 VS 2025 VS 2032) & (US$ Million)
- 2.3.2 500 IU/Vial
- 2.3.3 600 IU/Vial
- 2.3.4 1000 IU/Vial
- 2.3.5 Others
- 2.4 Human Prothrombin Complex by Application
- 2.4.1 Market Value Comparison by Application (2021 VS 2025 VS 2032)
- 2.4.2 Hemophilia B
- 2.4.3 Vitamin K Deficiency
- 2.4.4 Others
3 Market Competitive Landscape by Manufacturers
- 3.1 Global Human Prothrombin Complex Market Competitive Situation by Manufacturers (2021 Versus 2025)
- 3.2 Global Human Prothrombin Complex Sales (K Units) of Manufacturers (2021-2026)
- 3.3 Global Human Prothrombin Complex Revenue of Manufacturers (2021-2026)
- 3.4 Global Human Prothrombin Complex Average Price by Manufacturers (2021-2026)
- 3.5 Global Human Prothrombin Complex Industry Ranking, 2024 VS 2025 VS 2026
- 3.6 Global Manufacturers of Human Prothrombin Complex, Manufacturing Sites & Headquarters
- 3.7 Global Manufacturers of Human Prothrombin Complex, Product Type & Application
- 3.8 Global Manufacturers of Human Prothrombin Complex, Established Date
- 3.9 Global Human Prothrombin Complex Market CR5 and HHI
- 3.10 Global Manufacturers Mergers & Acquisition
4 Manufacturers Profiled
- 4.1 Takeda
- 4.1.1 Takeda Company Information
- 4.1.2 Takeda Business Overview
- 4.1.3 Takeda Human Prothrombin Complex Sales, Revenue and Gross Margin (2021-2026)
- 4.1.4 Takeda Human Prothrombin Complex Product Portfolio
- 4.1.5 Takeda Recent Developments
- 4.2 CSL
- 4.2.1 CSL Company Information
- 4.2.2 CSL Business Overview
- 4.2.3 CSL Human Prothrombin Complex Sales, Revenue and Gross Margin (2021-2026)
- 4.2.4 CSL Human Prothrombin Complex Product Portfolio
- 4.2.5 CSL Recent Developments
- 4.3 Grifols
- 4.3.1 Grifols Company Information
- 4.3.2 Grifols Business Overview
- 4.3.3 Grifols Human Prothrombin Complex Sales, Revenue and Gross Margin (2021-2026)
- 4.3.4 Grifols Human Prothrombin Complex Product Portfolio
- 4.3.5 Grifols Recent Developments
- 4.4 Octapharma
- 4.4.1 Octapharma Company Information
- 4.4.2 Octapharma Business Overview
- 4.4.3 Octapharma Human Prothrombin Complex Sales, Revenue and Gross Margin (2021-2026)
- 4.4.4 Octapharma Human Prothrombin Complex Product Portfolio
- 4.4.5 Octapharma Recent Developments
- 4.5 Hualan Biological
- 4.5.1 Hualan Biological Company Information
- 4.5.2 Hualan Biological Business Overview
- 4.5.3 Hualan Biological Human Prothrombin Complex Sales, Revenue and Gross Margin (2021-2026)
- 4.5.4 Hualan Biological Human Prothrombin Complex Product Portfolio
- 4.5.5 Hualan Biological Recent Developments
- 4.6 Meheco Xinxing Pharma
- 4.6.1 Meheco Xinxing Pharma Company Information
- 4.6.2 Meheco Xinxing Pharma Business Overview
- 4.6.3 Meheco Xinxing Pharma Human Prothrombin Complex Sales, Revenue and Gross Margin (2021-2026)
- 4.6.4 Meheco Xinxing Pharma Human Prothrombin Complex Product Portfolio
- 4.6.5 Meheco Xinxing Pharma Recent Developments
5 Global Human Prothrombin Complex Market Scenario by Region
- 5.1 Global Human Prothrombin Complex Market Size by Region: 2021 VS 2025 VS 2032
- 5.2 Global Human Prothrombin Complex Sales by Region: 2021-2032
- 5.2.1 Global Human Prothrombin Complex Sales by Region: 2021-2026
- 5.2.2 Global Human Prothrombin Complex Sales by Region: 2027-2032
- 5.3 Global Human Prothrombin Complex Revenue by Region: 2021-2032
- 5.3.1 Global Human Prothrombin Complex Revenue by Region: 2021-2026
- 5.3.2 Global Human Prothrombin Complex Revenue by Region: 2027-2032
- 5.4 North America Human Prothrombin Complex Market Facts & Figures by Country
- 5.4.1 North America Human Prothrombin Complex Market Size by Country: 2021 VS 2025 VS 2032
- 5.4.2 North America Human Prothrombin Complex Sales by Country (2021-2032)
- 5.4.3 North America Human Prothrombin Complex Revenue by Country (2021-2032)
- 5.4.4 United States
- 5.4.5 Canada
- 5.4.6 Mexico
- 5.5 Europe Human Prothrombin Complex Market Facts & Figures by Country
- 5.5.1 Europe Human Prothrombin Complex Market Size by Country: 2021 VS 2025 VS 2032
- 5.5.2 Europe Human Prothrombin Complex Sales by Country (2021-2032)
- 5.5.3 Europe Human Prothrombin Complex Revenue by Country (2021-2032)
- 5.5.4 Germany
- 5.5.5 France
- 5.5.6 U.K.
- 5.5.7 Italy
- 5.5.8 Russia
- 5.5.9 Spain
- 5.5.10 Netherlands
- 5.5.11 Switzerland
- 5.5.12 Sweden
- 5.5.13 Poland
- 5.6 Asia Pacific Human Prothrombin Complex Market Facts & Figures by Country
- 5.6.1 Asia Pacific Human Prothrombin Complex Market Size by Country: 2021 VS 2025 VS 2032
- 5.6.2 Asia Pacific Human Prothrombin Complex Sales by Country (2021-2032)
- 5.6.3 Asia Pacific Human Prothrombin Complex Revenue by Country (2021-2032)
- 5.6.4 China
- 5.6.5 Japan
- 5.6.6 South Korea
- 5.6.7 India
- 5.6.8 Australia
- 5.6.9 Taiwan
- 5.6.10 Southeast Asia
- 5.7 South America Human Prothrombin Complex Market Facts & Figures by Country
- 5.7.1 South America Human Prothrombin Complex Market Size by Country: 2021 VS 2025 VS 2032
- 5.7.2 South America Human Prothrombin Complex Sales by Country (2021-2032)
- 5.7.3 South America Human Prothrombin Complex Revenue by Country (2021-2032)
- 5.7.4 Brazil
- 5.7.5 Argentina
- 5.7.6 Chile
- 5.8 Middle East and Africa Human Prothrombin Complex Market Facts & Figures by Country
- 5.8.1 Middle East and Africa Human Prothrombin Complex Market Size by Country: 2021 VS 2025 VS 2032
- 5.8.2 Middle East and Africa Human Prothrombin Complex Sales by Country (2021-2032)
- 5.8.3 Middle East and Africa Human Prothrombin Complex Revenue by Country (2021-2032)
- 5.8.4 Egypt
- 5.8.5 South Africa
- 5.8.6 Israel
- 5.8.7 Türkiye
- 5.8.8 GCC Countries
6 Segment by Type
- 6.1 Global Human Prothrombin Complex Sales by Type (2021-2032)
- 6.1.1 Global Human Prothrombin Complex Sales by Type (2021-2032) & (K Units)
- 6.1.2 Global Human Prothrombin Complex Sales Market Share by Type (2021-2032)
- 6.2 Global Human Prothrombin Complex Revenue by Type (2021-2032)
- 6.2.1 Global Human Prothrombin Complex Sales by Type (2021-2032) & (US$ Million)
- 6.2.2 Global Human Prothrombin Complex Revenue Market Share by Type (2021-2032)
- 6.3 Global Human Prothrombin Complex Price by Type (2021-2032)
7 Segment by Application
- 7.1 Global Human Prothrombin Complex Sales by Application (2021-2032)
- 7.1.1 Global Human Prothrombin Complex Sales by Application (2021-2032) & (K Units)
- 7.1.2 Global Human Prothrombin Complex Sales Market Share by Application (2021-2032)
- 7.2 Global Human Prothrombin Complex Revenue by Application (2021-2032)
- 7.2.1 Global Human Prothrombin Complex Sales by Application (2021-2032) & (US$ Million)
- 7.2.2 Global Human Prothrombin Complex Revenue Market Share by Application (2021-2032)
- 7.3 Global Human Prothrombin Complex Price by Application (2021-2032)
8 Value Chain and Sales Channels Analysis of the Market
- 8.1 Human Prothrombin Complex Value Chain Analysis
- 8.1.1 Human Prothrombin Complex Key Raw Materials
- 8.1.2 Raw Materials Key Suppliers
- 8.1.3 Human Prothrombin Complex Production Mode & Process
- 8.2 Human Prothrombin Complex Sales Channels Analysis
- 8.2.1 Direct Comparison with Distribution Share
- 8.2.2 Human Prothrombin Complex Distributors
- 8.2.3 Human Prothrombin Complex Customers
9 Global Human Prothrombin Complex Analyzing Market Dynamics
- 9.1 Human Prothrombin Complex Industry Trends
- 9.2 Human Prothrombin Complex Industry Drivers
- 9.3 Human Prothrombin Complex Industry Opportunities and Challenges
- 9.4 Human Prothrombin Complex Industry Restraints
10 Report Conclusion
11 Disclaimer
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