APO RESEARCH · REPORT
Trazodone Hydrochloride (API)
Trazodone, a phenylpiperazine–triazolopyridine antidepressant, was originally discovered and developed in Italy in the 1970s by Angelini research laboratories. Trazodone is used to treat depression and to treat the combination of symptoms of anxiety and depression. Like most antidepressants, trazodone has also been used in limited numbers of patients to treat panic disorder, obsessive-compulsive disorder, attention-deficit/hyperactivity disorder, enuresis (bed-wetting), eating disorders such as bulimia nervosa, cocaine dependency, and the depressive phase of bipolar (manic-depressive) disorder. It should be noted, however, that trazodone has not received official approval from the United States Food and Drug Administration (FDA) for these secondary uses.
Product & engineering
Understand the product.
Trazodone, a phenylpiperazine–triazolopyridine antidepressant, was originally discovered and developed in Italy in the 1970s by Angelini research laboratories. Trazodone is used to treat depression and to treat the combination of symptoms of anxiety and depression. Like most antidepressants, trazodone has also been used in limited numbers of patients to treat panic disorder, obsessive-compulsive disorder, attention-deficit/hyperactivity disorder, enuresis (bed-wetting), eating disorders such as bulimia nervosa, cocaine dependency, and the depressive phase of bipolar (manic-depressive) disorder. It should be noted, however, that trazodone has not received official approval from the United States Food and Drug Administration (FDA) for these secondary uses.
Trazodone hydrochloride is an antidepressant chemically unrelated to tricyclic, tetracyclic, or other known antidepressant agents. Trazodone hydrochloride is a triazolopyridine derivative designated as 2-[3-[4-(3-chlorophenyl)-1-piperazinyl] propyl]-1,2,4-triazolo[4,3-a]pyridin-3 (2H)-one hydrochloride. It is a white odorless crystalline powder which is freely soluble in water.
This report covers Trazodone Hydrochloride (API) (CAS Number: 25332-39-2) and Trazodone API (CAS Number: 19794-93-5).
Selected research
Industry Growth & Trends
Global Trazodone Hydrochloride (API) Industry Growth and Trends Forecast to 2032
Market perspective
Trazodone, a phenylpiperazine–triazolopyridine antidepressant, was originally discovered and developed in Italy in the 1970s by Angelini research laboratories. Trazodone is used to treat depression and to treat the combination of symptoms of anxiety and depression. Like most antidepressants, trazodone has also been used in limited numbers of patients to treat panic disorder, obsessive-compulsive disorder, attention-deficit/hyperactivity disorder, enuresis (bed-wetting), eating disorders such as bulimia nervosa, cocaine dependency, and the depressive phase of bipolar (manic-depressive) disorder. It should be noted, however, that trazodone has not received official approval from the United States Food and Drug Administration (FDA) for these secondary uses.
Trazodone hydrochloride is an antidepressant chemically unrelated to tricyclic, tetracyclic, or other known antidepressant agents. Trazodone hydrochloride is a triazolopyridine derivative designated as 2-[3-[4-(3-chlorophenyl)-1-piperazinyl] propyl]-1,2,4-triazolo[4,3-a]pyridin-3 (2H)-one hydrochloride. It is a white odorless crystalline powder which is freely soluble in water.
This report covers Trazodone Hydrochloride (API) (CAS Number: 25332-39-2) and Trazodone API (CAS Number: 19794-93-5).
Read the full market overview
Trazodone hydrochloride (API) consumed in USA are mostly imported from overseas. Major companies are Angelini, Mylan, SST Corporation, The Piramal Group. The sales market share of the four companies has reached 53%. The local factory, Teva occupied about 40% market share.
Report Scope
This report provides a structured, data-driven view of the global Trazodone Hydrochloride (API) market, combining harmonized quantitative metrics with targeted qualitative insight to support business and growth strategy, market positioning, and capital allocation.
The Trazodone Hydrochloride (API) market size, estimates, and forecasts are presented in terms of sales volume (Kg) and revenue (US$ million), with 2025 as the base year and historical and forecast data for 2021-2032. The report segments the global Trazodone Hydrochloride (API) market by Type, Application, region/country, and company, provides regional market sizes at the segment level, profiles the competitive landscape and key players and their market ranks, and reviews technology trends and new product developments relevant to Trazodone Hydrochloride (API).
Key Companies & Market Share Insights
This section analyzes the strategies and performance of leading manufacturers in the global Trazodone Hydrochloride (API) market, including portfolio focus, innovation and product development, mergers and acquisitions, collaborations, and geographic expansion used to sustain or enhance competitive positions. It also summarizes recent corporate developments and key financial indicators and provides global revenue, price, and sales volume data by manufacturer for 2020-2025, enabling benchmarking of scale, pricing, and market share and supporting assessment of market concentration through indicators such as CR5 and CR10.
Trazodone Hydrochloride (API) Market by Company
Teva
Angelini
Mylan
Fermion
The Piramal Group
Trazodone Hydrochloride (API) Segment by Type
Trazodone Hydrochloride (API)
Others
Trazodone Hydrochloride (API) Segment by Application
Antidepression
Anxiolytic
Hypnotic
Others
Trazodone Hydrochloride (API) Segment by Region
North America
United States
Canada
Mexico
Europe
Germany
France
U.K.
Italy
Russia
Spain
Netherlands
Switzerland
Sweden
Poland
Asia-Pacific
China
Japan
South Korea
India
Australia
Taiwan
Southeast Asia
South America
Brazil
Argentina
Chile
Middle East & Africa
Egypt
South Africa
Israel
Türkiye
GCC Countries
Key Drivers & Barriers
High-impact rendering factors and drivers have been studied in this report to aid the readers to understand the general development. Moreover, the report includes restraints and challenges that may act as stumbling blocks on the way of the players. This will assist the users to be attentive and make informed decisions related to business. Specialists have also laid their focus on the upcoming business prospects.
Reasons to Buy This Report
1. This report will help the readers to understand the competition within the industries and strategies for the competitive environment to enhance the potential profit. The report also focuses on the competitive landscape of the global Trazodone Hydrochloride (API) market, and introduces in detail the market share, industry ranking, competitor ecosystem, market performance, new product development, operation situation, expansion, and acquisition. etc. of the main players, which helps the readers to identify the main competitors and deeply understand the competition pattern of the market.
2. This report will help stakeholders to understand the global industry status and trends of Trazodone Hydrochloride (API) and provides them with information on key market drivers, restraints, challenges, and opportunities.
3. This report will help stakeholders to understand competitors better and gain more insights to strengthen their position in their businesses. The competitive landscape section includes the market share and rank (in volume and value), competitor ecosystem, new product development, expansion, and acquisition.
4. This report stays updated with novel technology integration, features, and the latest developments in the market.
5. This report helps stakeholders to gain insights into which regions to target globally.
6. This report helps stakeholders to gain insights into the end-user perception concerning the adoption of Trazodone Hydrochloride (API).
7. This report helps stakeholders to identify some of the key players in the market and understand their valuable contribution.
Chapter Outline
Chapter 1: Introduces the study scope of this report, executive summary of market segments by type, market size segments for North America, Europe, Asia Pacific, South America, Middle East & Africa.
Chapter 2: Introduces the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.
Chapter 3: Detailed analysis of Trazodone Hydrochloride (API) manufacturers competitive landscape, price, sales, revenue, market share and ranking, latest development plan, merger, and acquisition information, etc.
Chapter 4: Sales, revenue of Trazodone Hydrochloride (API) in regional level. It provides a quantitative analysis of the market size and development potential of each region and introduces the future development prospects, and market space in the world.
Chapter 5: Introduces market segments by application, market size segment for North America, Europe, Asia Pacific, South America, Middle East & Africa.
Chapter 6: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product sales, revenue, price, gross margin, product introduction, recent development, etc.
Chapter 7, 8, 9, 10 and 11: North America, Europe, Asia Pacific, South America, Middle East & Africa, sales and revenue by country.
Chapter 12: Analysis of industrial chain, key raw materials, manufacturing cost, and market dynamics.
Chapter 13: Concluding Insights of the report.
More report detail
Tables and figures
Scope & coverage.
Types
- Trazodone Hydrochloride (API)
- Others
Applications
- Antidepression
- Anxiolytic
- Hypnotic
- Others
Companies covered
- Teva
- Angelini
- Mylan
- Fermion
- The Piramal Group
Inside the report.
1 Market Overview
- 1.1 Product Definition
- 1.2 Global Market Growth Prospects
- 1.2.1 Global Trazodone Hydrochloride (API) Market Size Estimates and Forecasts (2021-2032)
- 1.2.2 Global Trazodone Hydrochloride (API) Sales Estimates and Forecasts (2021-2032)
- 1.3 Trazodone Hydrochloride (API) Market by Type
- 1.3.1 Trazodone Hydrochloride (API)
- 1.3.2 Others
- 1.4 Global Trazodone Hydrochloride (API) Market Size by Type
- 1.4.1 Global Trazodone Hydrochloride (API) Market Size Overview by Type (2021-2032)
- 1.4.2 Global Trazodone Hydrochloride (API) Historic Market Size Review by Type (2021-2026)
- 1.4.3 Global Trazodone Hydrochloride (API) Forecasted Market Size by Type (2027-2032)
- 1.5 Key Regions Market Size by Type
- 1.5.1 North America Trazodone Hydrochloride (API) Sales Breakdown by Type (2021-2026)
- 1.5.2 Europe Trazodone Hydrochloride (API) Sales Breakdown by Type (2021-2026)
- 1.5.3 Asia-Pacific Trazodone Hydrochloride (API) Sales Breakdown by Type (2021-2026)
- 1.5.4 South America Trazodone Hydrochloride (API) Sales Breakdown by Type (2021-2026)
- 1.5.5 Middle East and Africa Trazodone Hydrochloride (API) Sales Breakdown by Type (2021-2026)
2 Global Market Dynamics
- 2.1 Trazodone Hydrochloride (API) Industry Trends
- 2.2 Trazodone Hydrochloride (API) Industry Drivers
- 2.3 Trazodone Hydrochloride (API) Industry Opportunities and Challenges
- 2.4 Trazodone Hydrochloride (API) Industry Restraints
3 Market Competitive Landscape by Company
- 3.1 Global Top Players by Trazodone Hydrochloride (API) Revenue (2021-2026)
- 3.2 Global Top Players by Trazodone Hydrochloride (API) Sales (2021-2026)
- 3.3 Global Top Players by Trazodone Hydrochloride (API) Price (2021-2026)
- 3.4 Global Trazodone Hydrochloride (API) Industry Company Ranking, 2024 VS 2025 VS 2026
- 3.5 Global Trazodone Hydrochloride (API) Major Company Production Sites & Headquarters
- 3.6 Global Trazodone Hydrochloride (API) Company, Product Type & Application
- 3.7 Global Trazodone Hydrochloride (API) Company Establishment Date
- 3.8 Market Competitive Analysis
- 3.8.1 Global Trazodone Hydrochloride (API) Market CR5 and HHI
- 3.8.2 Global Top 5 and 10 Trazodone Hydrochloride (API) Players Market Share by Revenue in 2025
- 3.8.3 2025 Trazodone Hydrochloride (API) Tier 1, Tier 2, and Tier 3
4 Trazodone Hydrochloride (API) Regional Status and Outlook
- 4.1 Global Trazodone Hydrochloride (API) Market Size and CAGR by Region: 2021 VS 2025 VS 2032
- 4.2 Global Trazodone Hydrochloride (API) Historic Market Size by Region
- 4.2.1 Global Trazodone Hydrochloride (API) Sales in Volume by Region (2021-2026)
- 4.2.2 Global Trazodone Hydrochloride (API) Sales in Value by Region (2021-2026)
- 4.2.3 Global Trazodone Hydrochloride (API) Sales (Volume & Value), Price and Gross Margin (2021-2026)
- 4.3 Global Trazodone Hydrochloride (API) Forecasted Market Size by Region
- 4.3.1 Global Trazodone Hydrochloride (API) Sales in Volume by Region (2027-2032)
- 4.3.2 Global Trazodone Hydrochloride (API) Sales in Value by Region (2027-2032)
- 4.3.3 Global Trazodone Hydrochloride (API) Sales (Volume & Value), Price and Gross Margin (2027-2032)
5 Trazodone Hydrochloride (API) by Application
- 5.1 Trazodone Hydrochloride (API) Market by Application
- 5.1.1 Antidepression
- 5.1.2 Anxiolytic
- 5.1.3 Hypnotic
- 5.1.4 Others
- 5.2 Global Trazodone Hydrochloride (API) Market Size by Application
- 5.2.1 Global Trazodone Hydrochloride (API) Market Size Overview by Application (2021-2032)
- 5.2.2 Global Trazodone Hydrochloride (API) Historic Market Size Review by Application (2021-2026)
- 5.2.3 Global Trazodone Hydrochloride (API) Forecasted Market Size by Application (2027-2032)
- 5.3 Key Regions Market Size by Application
- 5.3.1 North America Trazodone Hydrochloride (API) Sales Breakdown by Application (2021-2026)
- 5.3.2 Europe Trazodone Hydrochloride (API) Sales Breakdown by Application (2021-2026)
- 5.3.3 Asia-Pacific Trazodone Hydrochloride (API) Sales Breakdown by Application (2021-2026)
- 5.3.4 South America Trazodone Hydrochloride (API) Sales Breakdown by Application (2021-2026)
- 5.3.5 Middle East and Africa Trazodone Hydrochloride (API) Sales Breakdown by Application (2021-2026)
6 Company Profiles
- 6.1 Teva
- 6.1.1 Teva Company Information
- 6.1.2 Teva Business Overview
- 6.1.3 Teva Trazodone Hydrochloride (API) Sales, Revenue and Gross Margin (2021-2026)
- 6.1.4 Teva Trazodone Hydrochloride (API) Product Portfolio
- 6.1.5 Teva Recent Developments
- 6.2 Angelini
- 6.2.1 Angelini Company Information
- 6.2.2 Angelini Business Overview
- 6.2.3 Angelini Trazodone Hydrochloride (API) Sales, Revenue and Gross Margin (2021-2026)
- 6.2.4 Angelini Trazodone Hydrochloride (API) Product Portfolio
- 6.2.5 Angelini Recent Developments
- 6.3 Mylan
- 6.3.1 Mylan Company Information
- 6.3.2 Mylan Business Overview
- 6.3.3 Mylan Trazodone Hydrochloride (API) Sales, Revenue and Gross Margin (2021-2026)
- 6.3.4 Mylan Trazodone Hydrochloride (API) Product Portfolio
- 6.3.5 Mylan Recent Developments
- 6.4 Fermion
- 6.4.1 Fermion Company Information
- 6.4.2 Fermion Business Overview
- 6.4.3 Fermion Trazodone Hydrochloride (API) Sales, Revenue and Gross Margin (2021-2026)
- 6.4.4 Fermion Trazodone Hydrochloride (API) Product Portfolio
- 6.4.5 Fermion Recent Developments
- 6.5 The Piramal Group
- 6.5.1 The Piramal Group Company Information
- 6.5.2 The Piramal Group Business Overview
- 6.5.3 The Piramal Group Trazodone Hydrochloride (API) Sales, Revenue and Gross Margin (2021-2026)
- 6.5.4 The Piramal Group Trazodone Hydrochloride (API) Product Portfolio
- 6.5.5 The Piramal Group Recent Developments
7 North America by Country
- 7.1 North America Trazodone Hydrochloride (API) Sales by Country
- 7.1.1 North America Trazodone Hydrochloride (API) Sales Growth Rate (CAGR) by Country: 2021 VS 2025 VS 2032
- 7.1.2 North America Trazodone Hydrochloride (API) Sales by Country (2021-2026)
- 7.1.3 North America Trazodone Hydrochloride (API) Sales Forecast by Country (2027-2032)
- 7.2 North America Trazodone Hydrochloride (API) Market Size by Country
- 7.2.1 North America Trazodone Hydrochloride (API) Market Size Growth Rate (CAGR) by Country: 2021 VS 2025 VS 2032
- 7.2.2 North America Trazodone Hydrochloride (API) Market Size by Country (2021-2026)
- 7.2.3 North America Trazodone Hydrochloride (API) Market Size Forecast by Country (2027-2032)
8 Europe by Country
- 8.1 Europe Trazodone Hydrochloride (API) Sales by Country
- 8.1.1 Europe Trazodone Hydrochloride (API) Sales Growth Rate (CAGR) by Country: 2021 VS 2025 VS 2032
- 8.1.2 Europe Trazodone Hydrochloride (API) Sales by Country (2021-2026)
- 8.1.3 Europe Trazodone Hydrochloride (API) Sales Forecast by Country (2027-2032)
- 8.2 Europe Trazodone Hydrochloride (API) Market Size by Country
- 8.2.1 Europe Trazodone Hydrochloride (API) Market Size Growth Rate (CAGR) by Country: 2021 VS 2025 VS 2032
- 8.2.2 Europe Trazodone Hydrochloride (API) Market Size by Country (2021-2026)
- 8.2.3 Europe Trazodone Hydrochloride (API) Market Size Forecast by Country (2027-2032)
9 Asia-Pacific by Country
- 9.1 Asia-Pacific Trazodone Hydrochloride (API) Sales by Country
- 9.1.1 Asia-Pacific Trazodone Hydrochloride (API) Sales Growth Rate (CAGR) by Country: 2021 VS 2025 VS 2032
- 9.1.2 Asia-Pacific Trazodone Hydrochloride (API) Sales by Country (2021-2026)
- 9.1.3 Asia-Pacific Trazodone Hydrochloride (API) Sales Forecast by Country (2027-2032)
- 9.2 Asia-Pacific Trazodone Hydrochloride (API) Market Size by Country
- 9.2.1 Asia-Pacific Trazodone Hydrochloride (API) Market Size Growth Rate (CAGR) by Country: 2021 VS 2025 VS 2032
- 9.2.2 Asia-Pacific Trazodone Hydrochloride (API) Market Size by Country (2021-2026)
- 9.2.3 Asia-Pacific Trazodone Hydrochloride (API) Market Size Forecast by Country (2027-2032)
10 South America by Country
- 10.1 South America Trazodone Hydrochloride (API) Sales by Country
- 10.1.1 South America Trazodone Hydrochloride (API) Sales Growth Rate (CAGR) by Country: 2021 VS 2025 VS 2032
- 10.1.2 South America Trazodone Hydrochloride (API) Sales by Country (2021-2026)
- 10.1.3 South America Trazodone Hydrochloride (API) Sales Forecast by Country (2027-2032)
- 10.2 South America Trazodone Hydrochloride (API) Market Size by Country
- 10.2.1 South America Trazodone Hydrochloride (API) Market Size Growth Rate (CAGR) by Country: 2021 VS 2025 VS 2032
- 10.2.2 South America Trazodone Hydrochloride (API) Market Size by Country (2021-2026)
- 10.2.3 South America Trazodone Hydrochloride (API) Market Size Forecast by Country (2027-2032)
11 Middle East and Africa by Country
- 11.1 Middle East and Africa Trazodone Hydrochloride (API) Sales by Country
- 11.1.1 Middle East and Africa Trazodone Hydrochloride (API) Sales Growth Rate (CAGR) by Country: 2021 VS 2025 VS 2032
- 11.1.2 Middle East and Africa Trazodone Hydrochloride (API) Sales by Country (2021-2026)
- 11.1.3 Middle East and Africa Trazodone Hydrochloride (API) Sales Forecast by Country (2027-2032)
- 11.2 Middle East and Africa Trazodone Hydrochloride (API) Market Size by Country
- 11.2.1 Middle East and Africa Trazodone Hydrochloride (API) Market Size Growth Rate (CAGR) by Country: 2021 VS 2025 VS 2032
- 11.2.2 Middle East and Africa Trazodone Hydrochloride (API) Market Size by Country (2021-2026)
- 11.2.3 Middle East and Africa Trazodone Hydrochloride (API) Market Size Forecast by Country (2027-2032)
12 Value Chain and Sales Channels Analysis
- 12.1 Trazodone Hydrochloride (API) Value Chain Analysis
- 12.1.1 Trazodone Hydrochloride (API) Key Raw Materials
- 12.1.2 Key Raw Materials Price
- 12.1.3 Raw Materials Key Suppliers
- 12.1.4 Manufacturing Cost Structure
- 12.1.5 Trazodone Hydrochloride (API) Production Mode & Process
- 12.2 Trazodone Hydrochloride (API) Sales Channels Analysis
- 12.2.1 Direct Comparison with Distribution Share
- 12.2.2 Trazodone Hydrochloride (API) Distributors
- 12.2.3 Trazodone Hydrochloride (API) Customers
13 Concluding Insights
14 Appendix
- 14.1 Reasons for Doing This Study
- 14.2 Research Methodology
- 14.3 Research Process
- 14.4 Authors List of This Report
- 14.5 Data Source
- 14.5.1 Secondary Sources
- 14.5.2 Primary Sources
- 14.6 Disclaimer
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