APO RESEARCH · REPORT
Trazodone Hydrochloride (API)
Trazodone, a phenylpiperazine–triazolopyridine antidepressant, was originally discovered and developed in Italy in the 1970s by Angelini research laboratories. Trazodone is used to treat depression and to treat the combination of symptoms of anxiety and depression. Like most antidepressants, trazodone has also been used in limited numbers of patients to treat panic disorder, obsessive-compulsive disorder, attention-deficit/hyperactivity disorder, enuresis (bed-wetting), eating disorders such as bulimia nervosa, cocaine dependency, and the depressive phase of bipolar (manic-depressive) disorder. It should be noted, however, that trazodone has not received official approval from the United States Food and Drug Administration (FDA) for these secondary uses.
Product & engineering
Understand the product.
Trazodone, a phenylpiperazine–triazolopyridine antidepressant, was originally discovered and developed in Italy in the 1970s by Angelini research laboratories. Trazodone is used to treat depression and to treat the combination of symptoms of anxiety and depression. Like most antidepressants, trazodone has also been used in limited numbers of patients to treat panic disorder, obsessive-compulsive disorder, attention-deficit/hyperactivity disorder, enuresis (bed-wetting), eating disorders such as bulimia nervosa, cocaine dependency, and the depressive phase of bipolar (manic-depressive) disorder. It should be noted, however, that trazodone has not received official approval from the United States Food and Drug Administration (FDA) for these secondary uses.
Trazodone hydrochloride is an antidepressant chemically unrelated to tricyclic, tetracyclic, or other known antidepressant agents. Trazodone hydrochloride is a triazolopyridine derivative designated as 2-[3-[4-(3-chlorophenyl)-1-piperazinyl] propyl]-1,2,4-triazolo[4,3-a]pyridin-3 (2H)-one hydrochloride. It is a white odorless crystalline powder which is freely soluble in water.
This report covers Trazodone Hydrochloride (API) (CAS Number: 25332-39-2) and Trazodone API (CAS Number: 19794-93-5).
Selected research
Industry Research
Trazodone Hydrochloride (API) Industry Research Report 2026
Market perspective
Trazodone, a phenylpiperazine–triazolopyridine antidepressant, was originally discovered and developed in Italy in the 1970s by Angelini research laboratories. Trazodone is used to treat depression and to treat the combination of symptoms of anxiety and depression. Like most antidepressants, trazodone has also been used in limited numbers of patients to treat panic disorder, obsessive-compulsive disorder, attention-deficit/hyperactivity disorder, enuresis (bed-wetting), eating disorders such as bulimia nervosa, cocaine dependency, and the depressive phase of bipolar (manic-depressive) disorder. It should be noted, however, that trazodone has not received official approval from the United States Food and Drug Administration (FDA) for these secondary uses.
Trazodone hydrochloride is an antidepressant chemically unrelated to tricyclic, tetracyclic, or other known antidepressant agents. Trazodone hydrochloride is a triazolopyridine derivative designated as 2-[3-[4-(3-chlorophenyl)-1-piperazinyl] propyl]-1,2,4-triazolo[4,3-a]pyridin-3 (2H)-one hydrochloride. It is a white odorless crystalline powder which is freely soluble in water.
This report covers Trazodone Hydrochloride (API) (CAS Number: 25332-39-2) and Trazodone API (CAS Number: 19794-93-5).
Read the full market overview
Trazodone hydrochloride (API) consumed in USA are mostly imported from overseas. Major companies are Angelini, Mylan, SST Corporation, The Piramal Group. The sales market share of the four companies has reached 53%. The local factory, Teva occupied about 40% market share.
Report Scope
This report quantifies the global Trazodone Hydrochloride (API) market in terms of revenue (US$ million) and, where applicable, sales volume (Kg), using 2025 as the base year and providing annual historical and forecast data for 2021–2032.
It standardizes definitions of Types and Applications, harmonizes vendor attribution, and presents comparable time series by company, Type, Application, and region/country, including indicative price bands (US$/Kg) and concentration ratios (CR5/CR10).
The outputs are intended to support strategy development, budgeting, and performance benchmarking for brand owners, manufacturers, retailers, channel partners, and investors; data are structured with consistent units and fields to facilitate integration into internal FP&A and BI systems.
Key Companies & Market Share Insights
This section profiles leading manufacturers, combining 2021–2025 results with a 2026–2032 outlook. It reports revenue, market share, price bands, product and application mix, regional and channel mix, and key developments (M&A, capacity additions, certifications). It also provides global revenue, average price, and—where applicable—sales volume by manufacturer, and calculates CR5/CR10 and rank changes to support comparative benchmarking.
Trazodone Hydrochloride (API) Market by Company
Teva
Angelini
Mylan
Fermion
The Piramal Group
Trazodone Hydrochloride (API) Segment by Type
Trazodone Hydrochloride (API)
Others
Trazodone Hydrochloride (API) Segment by Application
Antidepression
Anxiolytic
Hypnotic
Others
Trazodone Hydrochloride (API) Segment by Region
North America
United States
Canada
Mexico
Europe
Germany
France
U.K.
Italy
Russia
Spain
Netherlands
Switzerland
Sweden
Poland
Asia-Pacific
China
Japan
South Korea
India
Australia
Taiwan
Southeast Asia
South America
Brazil
Argentina
Chile
Middle East & Africa
Egypt
South Africa
Israel
Türkiye
GCC Countries
Key Drivers & Barriers
High-impact rendering factors and drivers have been studied in this report to aid the readers to understand the general development. Moreover, the report includes restraints and challenges that may act as stumbling blocks on the way of the players. This will assist the users to be attentive and make informed decisions related to business. Specialists have also laid their focus on the upcoming business prospects.
Reasons to Buy This Report
1. This report will help the readers to understand the competition within the industries and strategies for the competitive environment to enhance the potential profit. The report also focuses on the competitive landscape of the global Trazodone Hydrochloride (API) market, and introduces in detail the market share, industry ranking, competitor ecosystem, market performance, new product development, operation situation, expansion, and acquisition. etc. of the main players, which helps the readers to identify the main competitors and deeply understand the competition pattern of the market.
2. This report will help stakeholders to understand the global industry status and trends of Trazodone Hydrochloride (API) and provides them with information on key market drivers, restraints, challenges, and opportunities.
3. This report will help stakeholders to understand competitors better and gain more insights to strengthen their position in their businesses. The competitive landscape section includes the market share and rank (in volume and value), competitor ecosystem, new product development, expansion, and acquisition.
4. This report stays updated with novel technology integration, features, and the latest developments in the market
5. This report helps stakeholders to gain insights into which regions to target globally
6. This report helps stakeholders to gain insights into the end-user perception concerning the adoption of Trazodone Hydrochloride (API).
7. This report helps stakeholders to identify some of the key players in the market and understand their valuable contribution.
Chapter Outline
Chapter 1: Research objectives, research methods, data sources, data cross-validation;
Chapter 2: Introduces the report scope of the report, executive summary of different market segments (by region, product type, application, etc.), including the market size of each market segment, future development potential, and so on. It offers a high-level view of the current state of the market and its likely evolution in the short to mid-term, and long term.
Chapter 3: Detailed analysis of Trazodone Hydrochloride (API) manufacturers competitive landscape, price, production and value market share, latest development plan, merger, and acquisition information, etc.
Chapter 4: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product production/output, value, price, gross margin, product introduction, recent development, etc.
Chapter 5: Production/output, value of Trazodone Hydrochloride (API) by region/country. It provides a quantitative analysis of the market size and development potential of each region in the next six years.
Chapter 6: Consumption of Trazodone Hydrochloride (API) in regional level and country level. It provides a quantitative analysis of the market size and development potential of each region and its main countries and introduces the market development, future development prospects, market space, and production of each country in the world.
Chapter 7: Provides the analysis of various market segments by type, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.
Chapter 8: Provides the analysis of various market segments by application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.
Chapter 9: Analysis of industrial chain, including the upstream and downstream of the industry.
Chapter 10: Introduces the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.
Chapter 11: The main points and conclusions of the report.
More report detail
Tables and figures
Scope & coverage.
Types
- Trazodone Hydrochloride (API)
- Others
Applications
- Antidepression
- Anxiolytic
- Hypnotic
- Others
Companies covered
- Teva
- Angelini
- Mylan
- Fermion
- The Piramal Group
Inside the report.
1 Preface
- 1.1 Scope of Report
- 1.2 Reasons for Doing This Study
- 1.3 Research Methodology
- 1.4 Research Process
- 1.5 Data Source
- 1.5.1 Secondary Sources
- 1.5.2 Primary Sources
2 Market Overview
- 2.1 Product Definition
- 2.2 Global Market Growth Prospects
- 2.2.1 Global Trazodone Hydrochloride (API) Market Size (2021-2032)
- 2.2.2 Global Trazodone Hydrochloride (API) Sales (2021-2032)
- 2.2.3 Global Trazodone Hydrochloride (API) Market Average Price (2021-2032)
- 2.3 Trazodone Hydrochloride (API) by Type
- 2.3.1 Market Value Comparison by Type (2021 VS 2025 VS 2032) & (US$ Million)
- 2.3.2 Trazodone Hydrochloride (API)
- 2.3.3 Others
- 2.4 Trazodone Hydrochloride (API) by Application
- 2.4.1 Market Value Comparison by Application (2021 VS 2025 VS 2032)
- 2.4.2 Antidepression
- 2.4.3 Anxiolytic
- 2.4.4 Hypnotic
- 2.4.5 Others
3 Market Competitive Landscape by Manufacturers
- 3.1 Global Trazodone Hydrochloride (API) Market Competitive Situation by Manufacturers (2021 Versus 2025)
- 3.2 Global Trazodone Hydrochloride (API) Sales (Kg) of Manufacturers (2021-2026)
- 3.3 Global Trazodone Hydrochloride (API) Revenue of Manufacturers (2021-2026)
- 3.4 Global Trazodone Hydrochloride (API) Average Price by Manufacturers (2021-2026)
- 3.5 Global Trazodone Hydrochloride (API) Industry Ranking, 2024 VS 2025 VS 2026
- 3.6 Global Manufacturers of Trazodone Hydrochloride (API), Manufacturing Sites & Headquarters
- 3.7 Global Manufacturers of Trazodone Hydrochloride (API), Product Type & Application
- 3.8 Global Manufacturers of Trazodone Hydrochloride (API), Established Date
- 3.9 Global Trazodone Hydrochloride (API) Market CR5 and HHI
- 3.10 Global Manufacturers Mergers & Acquisition
4 Manufacturers Profiled
- 4.1 Teva
- 4.1.1 Teva Company Information
- 4.1.2 Teva Business Overview
- 4.1.3 Teva Trazodone Hydrochloride (API) Sales, Revenue and Gross Margin (2021-2026)
- 4.1.4 Teva Trazodone Hydrochloride (API) Product Portfolio
- 4.1.5 Teva Recent Developments
- 4.2 Angelini
- 4.2.1 Angelini Company Information
- 4.2.2 Angelini Business Overview
- 4.2.3 Angelini Trazodone Hydrochloride (API) Sales, Revenue and Gross Margin (2021-2026)
- 4.2.4 Angelini Trazodone Hydrochloride (API) Product Portfolio
- 4.2.5 Angelini Recent Developments
- 4.3 Mylan
- 4.3.1 Mylan Company Information
- 4.3.2 Mylan Business Overview
- 4.3.3 Mylan Trazodone Hydrochloride (API) Sales, Revenue and Gross Margin (2021-2026)
- 4.3.4 Mylan Trazodone Hydrochloride (API) Product Portfolio
- 4.3.5 Mylan Recent Developments
- 4.4 Fermion
- 4.4.1 Fermion Company Information
- 4.4.2 Fermion Business Overview
- 4.4.3 Fermion Trazodone Hydrochloride (API) Sales, Revenue and Gross Margin (2021-2026)
- 4.4.4 Fermion Trazodone Hydrochloride (API) Product Portfolio
- 4.4.5 Fermion Recent Developments
- 4.5 The Piramal Group
- 4.5.1 The Piramal Group Company Information
- 4.5.2 The Piramal Group Business Overview
- 4.5.3 The Piramal Group Trazodone Hydrochloride (API) Sales, Revenue and Gross Margin (2021-2026)
- 4.5.4 The Piramal Group Trazodone Hydrochloride (API) Product Portfolio
- 4.5.5 The Piramal Group Recent Developments
5 Global Trazodone Hydrochloride (API) Market Scenario by Region
- 5.1 Global Trazodone Hydrochloride (API) Market Size by Region: 2021 VS 2025 VS 2032
- 5.2 Global Trazodone Hydrochloride (API) Sales by Region: 2021-2032
- 5.2.1 Global Trazodone Hydrochloride (API) Sales by Region: 2021-2026
- 5.2.2 Global Trazodone Hydrochloride (API) Sales by Region: 2027-2032
- 5.3 Global Trazodone Hydrochloride (API) Revenue by Region: 2021-2032
- 5.3.1 Global Trazodone Hydrochloride (API) Revenue by Region: 2021-2026
- 5.3.2 Global Trazodone Hydrochloride (API) Revenue by Region: 2027-2032
- 5.4 North America Trazodone Hydrochloride (API) Market Facts & Figures by Country
- 5.4.1 North America Trazodone Hydrochloride (API) Market Size by Country: 2021 VS 2025 VS 2032
- 5.4.2 North America Trazodone Hydrochloride (API) Sales by Country (2021-2032)
- 5.4.3 North America Trazodone Hydrochloride (API) Revenue by Country (2021-2032)
- 5.4.4 United States
- 5.4.5 Canada
- 5.4.6 Mexico
- 5.5 Europe Trazodone Hydrochloride (API) Market Facts & Figures by Country
- 5.5.1 Europe Trazodone Hydrochloride (API) Market Size by Country: 2021 VS 2025 VS 2032
- 5.5.2 Europe Trazodone Hydrochloride (API) Sales by Country (2021-2032)
- 5.5.3 Europe Trazodone Hydrochloride (API) Revenue by Country (2021-2032)
- 5.5.4 Germany
- 5.5.5 France
- 5.5.6 U.K.
- 5.5.7 Italy
- 5.5.8 Russia
- 5.5.9 Spain
- 5.5.10 Netherlands
- 5.5.11 Switzerland
- 5.5.12 Sweden
- 5.5.13 Poland
- 5.6 Asia Pacific Trazodone Hydrochloride (API) Market Facts & Figures by Country
- 5.6.1 Asia Pacific Trazodone Hydrochloride (API) Market Size by Country: 2021 VS 2025 VS 2032
- 5.6.2 Asia Pacific Trazodone Hydrochloride (API) Sales by Country (2021-2032)
- 5.6.3 Asia Pacific Trazodone Hydrochloride (API) Revenue by Country (2021-2032)
- 5.6.4 China
- 5.6.5 Japan
- 5.6.6 South Korea
- 5.6.7 India
- 5.6.8 Australia
- 5.6.9 Taiwan
- 5.6.10 Southeast Asia
- 5.7 South America Trazodone Hydrochloride (API) Market Facts & Figures by Country
- 5.7.1 South America Trazodone Hydrochloride (API) Market Size by Country: 2021 VS 2025 VS 2032
- 5.7.2 South America Trazodone Hydrochloride (API) Sales by Country (2021-2032)
- 5.7.3 South America Trazodone Hydrochloride (API) Revenue by Country (2021-2032)
- 5.7.4 Brazil
- 5.7.5 Argentina
- 5.7.6 Chile
- 5.8 Middle East and Africa Trazodone Hydrochloride (API) Market Facts & Figures by Country
- 5.8.1 Middle East and Africa Trazodone Hydrochloride (API) Market Size by Country: 2021 VS 2025 VS 2032
- 5.8.2 Middle East and Africa Trazodone Hydrochloride (API) Sales by Country (2021-2032)
- 5.8.3 Middle East and Africa Trazodone Hydrochloride (API) Revenue by Country (2021-2032)
- 5.8.4 Egypt
- 5.8.5 South Africa
- 5.8.6 Israel
- 5.8.7 Türkiye
- 5.8.8 GCC Countries
6 Segment by Type
- 6.1 Global Trazodone Hydrochloride (API) Sales by Type (2021-2032)
- 6.1.1 Global Trazodone Hydrochloride (API) Sales by Type (2021-2032) & (Kg)
- 6.1.2 Global Trazodone Hydrochloride (API) Sales Market Share by Type (2021-2032)
- 6.2 Global Trazodone Hydrochloride (API) Revenue by Type (2021-2032)
- 6.2.1 Global Trazodone Hydrochloride (API) Sales by Type (2021-2032) & (US$ Million)
- 6.2.2 Global Trazodone Hydrochloride (API) Revenue Market Share by Type (2021-2032)
- 6.3 Global Trazodone Hydrochloride (API) Price by Type (2021-2032)
7 Segment by Application
- 7.1 Global Trazodone Hydrochloride (API) Sales by Application (2021-2032)
- 7.1.1 Global Trazodone Hydrochloride (API) Sales by Application (2021-2032) & (Kg)
- 7.1.2 Global Trazodone Hydrochloride (API) Sales Market Share by Application (2021-2032)
- 7.2 Global Trazodone Hydrochloride (API) Revenue by Application (2021-2032)
- 7.2.1 Global Trazodone Hydrochloride (API) Sales by Application (2021-2032) & (US$ Million)
- 7.2.2 Global Trazodone Hydrochloride (API) Revenue Market Share by Application (2021-2032)
- 7.3 Global Trazodone Hydrochloride (API) Price by Application (2021-2032)
8 Value Chain and Sales Channels Analysis of the Market
- 8.1 Trazodone Hydrochloride (API) Value Chain Analysis
- 8.1.1 Trazodone Hydrochloride (API) Key Raw Materials
- 8.1.2 Raw Materials Key Suppliers
- 8.1.3 Trazodone Hydrochloride (API) Production Mode & Process
- 8.2 Trazodone Hydrochloride (API) Sales Channels Analysis
- 8.2.1 Direct Comparison with Distribution Share
- 8.2.2 Trazodone Hydrochloride (API) Distributors
- 8.2.3 Trazodone Hydrochloride (API) Customers
9 Global Trazodone Hydrochloride (API) Analyzing Market Dynamics
- 9.1 Trazodone Hydrochloride (API) Industry Trends
- 9.2 Trazodone Hydrochloride (API) Industry Drivers
- 9.3 Trazodone Hydrochloride (API) Industry Opportunities and Challenges
- 9.4 Trazodone Hydrochloride (API) Industry Restraints
10 Report Conclusion
11 Disclaimer
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