APO RESEARCH · REPORT
Inhaled Nitric Oxide
Nitric oxide is a chemical compound in gas form that is sometimes used to treat infants with severe breathing problems associated with narrow blood vessels in the lungs. It works by relaxing smooth muscle to widen (dilate) blood vessels, especially in the lungs. Nitric oxide is usually used together with a breathing machine (ventilator).
Product & engineering
Understand the product.
Nitric oxide is a chemical compound in gas form that is sometimes used to treat infants with severe breathing problems associated with narrow blood vessels in the lungs. It works by relaxing smooth muscle to widen (dilate) blood vessels, especially in the lungs. Nitric oxide is usually used together with a breathing machine (ventilator).
Inhaled nitric oxide (iNO) is recognized as a potent and selective pulmonary vasodilator that does not decrease systemic vascular tone. The therapeutic application of iNO in human was first described in 1990s. INO therapy was effective to improve oxygenation in infants with persistent pulmonary hypertension of the newborn (PPHN). Owing to its selective pulmonary vasodilator effects, iNO therapy is an important treatment for term newborns with hypoxemic respiratory failure due to PPHN. The Food and Drug Administration of the United States of America first approved iNO in 1999 for use as a medical gas to treat hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension in term and late preterm neonates. Thereafter, iNO therapy is clinically applied to treat PPHN in term and late preterm neonates without consensus.
Selected research
Market Analysis & Forecast
Global Inhaled Nitric Oxide Market Analysis and Forecast 2026-2032
Market perspective
Nitric oxide is a chemical compound in gas form that is sometimes used to treat infants with severe breathing problems associated with narrow blood vessels in the lungs. It works by relaxing smooth muscle to widen (dilate) blood vessels, especially in the lungs. Nitric oxide is usually used together with a breathing machine (ventilator).
Inhaled nitric oxide (iNO) is recognized as a potent and selective pulmonary vasodilator that does not decrease systemic vascular tone. The therapeutic application of iNO in human was first described in 1990s. INO therapy was effective to improve oxygenation in infants with persistent pulmonary hypertension of the newborn (PPHN). Owing to its selective pulmonary vasodilator effects, iNO therapy is an important treatment for term newborns with hypoxemic respiratory failure due to PPHN. The Food and Drug Administration of the United States of America first approved iNO in 1999 for use as a medical gas to treat hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension in term and late preterm neonates. Thereafter, iNO therapy is clinically applied to treat PPHN in term and late preterm neonates without consensus.
Mallinckrodt monopolizes the global Inhaled Nitric Oxide market, holding a share about 65%.
Read the full market overview
North America is the largest market, with a share about 77%, followed by Asia-Pacific and Europe, have a share about 20 percent.
In terms of product, 800 ppm is the largest segment, with a share over 50%. And in terms of application, the largest application is Near-term and Pre-term Infants PPHN, followed by Children and Adult ARDS, etc.
This report presents an overview of global market for Inhaled Nitric Oxide, sales, revenue and price. Analyses of the global market trends, with historic market revenue or sales data for 2021 - 2025, estimates for 2026, and projections of CAGR through 2032.
This report researches the key producers of Inhaled Nitric Oxide, also provides the sales of main regions and countries. Of the upcoming market potential for Inhaled Nitric Oxide, and key regions or countries of focus to forecast this market into various segments and sub-segments. Country specific data and market value analysis for the U.S., Canada, Mexico, Brazil, China, Japan, South Korea, Southeast Asia, India, Germany, the U.K., Italy, Middle East, Africa, and Other Countries.
This report focuses on the Inhaled Nitric Oxide sales, revenue, market share and industry ranking of main manufacturers, data from 2021 to 2026. Identification of the major stakeholders in the global Inhaled Nitric Oxide market, and analysis of their competitive landscape and market positioning based on recent developments and segmental revenues. This report will help stakeholders to understand the competitive landscape and gain more insights and position their businesses and market strategies in a better way.
This report analyzes the segments data by Type and by Application, sales, revenue, and price, from 2021 to 2032. Evaluation and forecast the market size for Inhaled Nitric Oxide sales, projected growth trends, production technology, application and end-user industry.
Inhaled Nitric Oxide Segment by Company
Mallinckrodt
Praxair (Linde plc)
Air Liquide
BOC Healthcare (Linde Group)
Inhaled Nitric Oxide Segment by Type
800 ppm
100 ppm
Others
Inhaled Nitric Oxide Segment by Application
Near-term and Pre-term Infants PPHN
Children and Adult ARDS
Other Diseases
Inhaled Nitric Oxide Segment by Region
North America
United States
Canada
Mexico
Europe
Germany
France
U.K.
Italy
Russia
Spain
Netherlands
Switzerland
Sweden
Poland
Asia-Pacific
China
Japan
South Korea
India
Australia
Taiwan
Southeast Asia
South America
Brazil
Argentina
Chile
Middle East & Africa
Egypt
South Africa
Israel
Türkiye
GCC Countries
Study Objectives
1. To analyze and research the global status and future forecast, involving growth rate (CAGR), market share, historical and forecast.
2. To present the key manufacturers, sales, revenue, market share, and Recent Developments.
3. To split the breakdown data by regions, type, manufacturers, and Application.
4. To analyze the global and key regions market potential and advantage, opportunity and challenge, restraints, and risks.
5. To identify significant trends, drivers, influence factors in global and regions.
6. To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market.
Reasons to Buy This Report
1. This report will help the readers to understand the competition within the industries and strategies for the competitive environment to enhance the potential profit. The report also focuses on the competitive landscape of the global Inhaled Nitric Oxide market, and introduces in detail the market share, industry ranking, competitor ecosystem, market performance, new product development, operation situation, expansion, and acquisition. etc. of the main players, which helps the readers to identify the main competitors and deeply understand the competition pattern of the market.
2. This report will help stakeholders to understand the global industry status and trends of Inhaled Nitric Oxide and provides them with information on key market drivers, restraints, challenges, and opportunities.
3. This report will help stakeholders to understand competitors better and gain more insights to strengthen their position in their businesses. The competitive landscape section includes the market share and rank (in sales and value), competitor ecosystem, new product development, expansion, and acquisition.
4. This report stays updated with novel technology integration, features, and the latest developments in the market.
5. This report helps stakeholders to gain insights into which regions to target globally.
6. This report helps stakeholders to gain insights into the end-user perception concerning the adoption of Inhaled Nitric Oxide.
7. This report helps stakeholders to identify some of the key players in the market and understand their valuable contribution.
Chapter Outline
Chapter 1: Introduces the report scope of the report, executive summary of different market segments (by type and by application, etc), including the market size of each market segment, future development potential, and so on. It offers a high-level view of the current state of the market and its likely evolution in the short to mid-term, and long term.
Chapter 2: Introduces the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.
Chapter 3: Sales (consumption), revenue of Inhaled Nitric Oxide in global, regional level and country level. It provides a quantitative analysis of the market size and development potential of each region and its main countries and introduces the market development, future development prospects, market space of each country in the world.
Chapter 4: Detailed analysis of Inhaled Nitric Oxide manufacturers competitive landscape, price, sales, revenue, market share and industry ranking, latest development plan, merger, and acquisition information, etc.
Chapter 5: Provides the analysis of various market segments by type, covering the sales, revenue, average price, and development potential of each market segment, to help readers find the blue ocean market in different market segments.
Chapter 6: Provides the analysis of various market segments by application, covering the sales, revenue, average price, and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.
Chapter 7: Provides profiles of key manufacturers, introducing the basic situation of the main companies in the market in detail, including product descriptions and specifications, Inhaled Nitric Oxide sales, revenue, price, gross margin, and recent development, etc.
Chapter 8: North America by type, by application and by country, sales, and revenue for each segment.
Chapter 9: Europe by type, by application and by country, sales, and revenue for each segment.
Chapter 10: China type, by application, sales, and revenue for each segment.
Chapter 11: Asia (excluding China) type, by application and by region, sales, and revenue for each segment.
Chapter 12: South America, Middle East and Africa by type, by application and by country, sales, and revenue for each segment.
Chapter 13: Analysis of industrial chain, sales channel, key raw materials, distributors and customers.
Chapter 14: The main concluding insights of the report.
More report detail
Tables and figures
Scope & coverage.
Types
- 800 ppm
- 100 ppm
- Others
Applications
- Near-term and Pre-term Infants PPHN
- Children and Adult ARDS
- Other Diseases
Companies covered
- Mallinckrodt
- Praxair (Linde plc)
- Air Liquide
- BOC Healthcare (Linde Group)
Inside the report.
1 Market Overview
- 1.1 Product Definition
- 1.2 Inhaled Nitric Oxide Market by Type
- 1.2.1 Global Inhaled Nitric Oxide Market Size by Type, 2021 VS 2025 VS 2032
- 1.2.2 800 ppm
- 1.2.3 100 ppm
- 1.2.4 Others
- 1.3 Inhaled Nitric Oxide Market by Application
- 1.3.1 Global Inhaled Nitric Oxide Market Size by Application, 2021 VS 2025 VS 2032
- 1.3.2 Near-term and Pre-term Infants PPHN
- 1.3.3 Children and Adult ARDS
- 1.3.4 Other Diseases
- 1.4 Assumptions and Limitations
- 1.5 Study Goals and Objectives
2 Inhaled Nitric Oxide Market Dynamics
- 2.1 Inhaled Nitric Oxide Industry Trends
- 2.2 Inhaled Nitric Oxide Industry Drivers
- 2.3 Inhaled Nitric Oxide Industry Opportunities and Challenges
- 2.4 Inhaled Nitric Oxide Industry Restraints
3 Global Market Growth Prospects
- 3.1 Global Inhaled Nitric Oxide Revenue Estimates and Forecasts (2021-2032)
- 3.2 Global Inhaled Nitric Oxide Revenue by Region
- 3.2.1 Global Inhaled Nitric Oxide Revenue by Region: 2021 VS 2025 VS 2032
- 3.2.2 Global Inhaled Nitric Oxide Revenue by Region (2021-2026)
- 3.2.3 Global Inhaled Nitric Oxide Revenue by Region (2027-2032)
- 3.2.4 Global Inhaled Nitric Oxide Revenue Market Share by Region (2021-2032)
- 3.3 Global Inhaled Nitric Oxide Sales Estimates and Forecasts 2021-2032
- 3.4 Global Inhaled Nitric Oxide Sales by Region
- 3.4.1 Global Inhaled Nitric Oxide Sales by Region: 2021 VS 2025 VS 2032
- 3.4.2 Global Inhaled Nitric Oxide Sales by Region (2021-2026)
- 3.4.3 Global Inhaled Nitric Oxide Sales by Region (2027-2032)
- 3.4.4 Global Inhaled Nitric Oxide Sales Market Share by Region (2021-2032)
- 3.5 US & Canada & Mexico
- 3.6 Europe
- 3.7 China
- 3.8 Asia (Excluding China)
- 3.9 South America, Middle East and Africa
4 Market Competitive Landscape by Manufacturers
- 4.1 Global Inhaled Nitric Oxide Revenue by Manufacturers
- 4.1.1 Global Inhaled Nitric Oxide Revenue by Manufacturers (2021-2026)
- 4.1.2 Global Inhaled Nitric Oxide Revenue Market Share by Manufacturers (2021-2026)
- 4.1.3 Global Inhaled Nitric Oxide Manufacturers Revenue Share Top 10 and Top 5 in 2025
- 4.2 Global Inhaled Nitric Oxide Sales by Manufacturers
- 4.2.1 Global Inhaled Nitric Oxide Sales by Manufacturers (2021-2026)
- 4.2.2 Global Inhaled Nitric Oxide Sales Market Share by Manufacturers (2021-2026)
- 4.2.3 Global Inhaled Nitric Oxide Manufacturers Sales Share Top 10 and Top 5 in 2025
- 4.3 Global Inhaled Nitric Oxide Sales Price by Manufacturers (2021-2026)
- 4.4 Global Inhaled Nitric Oxide Key Manufacturers Ranking, 2024 VS 2025 VS 2026
- 4.5 Global Inhaled Nitric Oxide Key Manufacturers Manufacturing Sites & Headquarters
- 4.6 Global Inhaled Nitric Oxide Manufacturers, Product Type & Application
- 4.7 Global Inhaled Nitric Oxide Manufacturers' Establishment Date
- 4.8 Market Competitive Analysis
- 4.8.1 Global Inhaled Nitric Oxide Market CR5 and HHI
- 4.8.2 2025 Inhaled Nitric Oxide Tier 1, Tier 2, and Tier 3
5 Inhaled Nitric Oxide Market by Type
- 5.1 Global Inhaled Nitric Oxide Revenue by Type
- 5.1.1 Global Inhaled Nitric Oxide Revenue by Type (2021 VS 2025 VS 2032)
- 5.1.2 Global Inhaled Nitric Oxide Revenue by Type (2021-2032) & (US$ Million)
- 5.1.3 Global Inhaled Nitric Oxide Revenue Market Share by Type (2021-2032)
- 5.2 Global Inhaled Nitric Oxide Sales by Type
- 5.2.1 Global Inhaled Nitric Oxide Sales by Type (2021 VS 2025 VS 2032)
- 5.2.2 Global Inhaled Nitric Oxide Sales by Type (2021-2032) & (M L)
- 5.2.3 Global Inhaled Nitric Oxide Sales Market Share by Type (2021-2032)
- 5.3 Global Inhaled Nitric Oxide Price by Type
6 Inhaled Nitric Oxide Market by Application
- 6.1 Global Inhaled Nitric Oxide Revenue by Application
- 6.1.1 Global Inhaled Nitric Oxide Revenue by Application (2021 VS 2025 VS 2032)
- 6.1.2 Global Inhaled Nitric Oxide Revenue by Application (2021-2032) & (US$ Million)
- 6.1.3 Global Inhaled Nitric Oxide Revenue Market Share by Application (2021-2032)
- 6.2 Global Inhaled Nitric Oxide Sales by Application
- 6.2.1 Global Inhaled Nitric Oxide Sales by Application (2021 VS 2025 VS 2032)
- 6.2.2 Global Inhaled Nitric Oxide Sales by Application (2021-2032) & (M L)
- 6.2.3 Global Inhaled Nitric Oxide Sales Market Share by Application (2021-2032)
- 6.3 Global Inhaled Nitric Oxide Price by Application
7 Company Profiles
- 7.1 Mallinckrodt
- 7.1.1 Mallinckrodt Company Information
- 7.1.2 Mallinckrodt Business Overview
- 7.1.3 Mallinckrodt Inhaled Nitric Oxide Sales, Revenue, Price and Gross Margin (2021-2026)
- 7.1.4 Mallinckrodt Inhaled Nitric Oxide Product Portfolio
- 7.1.5 Mallinckrodt Recent Developments
- 7.2 Praxair (Linde plc)
- 7.2.1 Praxair (Linde plc) Company Information
- 7.2.2 Praxair (Linde plc) Business Overview
- 7.2.3 Praxair (Linde plc) Inhaled Nitric Oxide Sales, Revenue, Price and Gross Margin (2021-2026)
- 7.2.4 Praxair (Linde plc) Inhaled Nitric Oxide Product Portfolio
- 7.2.5 Praxair (Linde plc) Recent Developments
- 7.3 Air Liquide
- 7.3.1 Air Liquide Company Information
- 7.3.2 Air Liquide Business Overview
- 7.3.3 Air Liquide Inhaled Nitric Oxide Sales, Revenue, Price and Gross Margin (2021-2026)
- 7.3.4 Air Liquide Inhaled Nitric Oxide Product Portfolio
- 7.3.5 Air Liquide Recent Developments
- 7.4 BOC Healthcare (Linde Group)
- 7.4.1 BOC Healthcare (Linde Group) Company Information
- 7.4.2 BOC Healthcare (Linde Group) Business Overview
- 7.4.3 BOC Healthcare (Linde Group) Inhaled Nitric Oxide Sales, Revenue, Price and Gross Margin (2021-2026)
- 7.4.4 BOC Healthcare (Linde Group) Inhaled Nitric Oxide Product Portfolio
- 7.4.5 BOC Healthcare (Linde Group) Recent Developments
8 North America
- 8.1 North America Inhaled Nitric Oxide Market Size by Type
- 8.1.1 North America Inhaled Nitric Oxide Revenue by Type (2021-2032)
- 8.1.2 North America Inhaled Nitric Oxide Sales by Type (2021-2032)
- 8.1.3 North America Inhaled Nitric Oxide Price by Type (2021-2032)
- 8.2 North America Inhaled Nitric Oxide Market Size by Application
- 8.2.1 North America Inhaled Nitric Oxide Revenue by Application (2021-2032)
- 8.2.2 North America Inhaled Nitric Oxide Sales by Application (2021-2032)
- 8.2.3 North America Inhaled Nitric Oxide Price by Application (2021-2032)
- 8.3 North America Inhaled Nitric Oxide Market Size by Country
- 8.3.1 North America Inhaled Nitric Oxide Revenue Grow Rate by Country (2021 VS 2025 VS 2032)
- 8.3.2 North America Inhaled Nitric Oxide Sales by Country (2021 VS 2025 VS 2032)
- 8.3.3 North America Inhaled Nitric Oxide Price by Country (2021-2032)
- 8.3.4 United States
- 8.3.5 Canada
- 8.3.6 Mexico
9 Europe
- 9.1 Europe Inhaled Nitric Oxide Market Size by Type
- 9.1.1 Europe Inhaled Nitric Oxide Revenue by Type (2021-2032)
- 9.1.2 Europe Inhaled Nitric Oxide Sales by Type (2021-2032)
- 9.1.3 Europe Inhaled Nitric Oxide Price by Type (2021-2032)
- 9.2 Europe Inhaled Nitric Oxide Market Size by Application
- 9.2.1 Europe Inhaled Nitric Oxide Revenue by Application (2021-2032)
- 9.2.2 Europe Inhaled Nitric Oxide Sales by Application (2021-2032)
- 9.2.3 Europe Inhaled Nitric Oxide Price by Application (2021-2032)
- 9.3 Europe Inhaled Nitric Oxide Market Size by Country
- 9.3.1 Europe Inhaled Nitric Oxide Revenue Grow Rate by Country (2021 VS 2025 VS 2032)
- 9.3.2 Europe Inhaled Nitric Oxide Sales by Country (2021 VS 2025 VS 2032)
- 9.3.3 Europe Inhaled Nitric Oxide Price by Country (2021-2032)
- 9.3.4 Germany
- 9.3.5 France
- 9.3.6 U.K.
- 9.3.7 Italy
- 9.3.8 Russia
- 9.3.9 Spain
- 9.3.10 Netherlands
10 China
- 10.1 China Inhaled Nitric Oxide Market Size by Type
- 10.1.1 China Inhaled Nitric Oxide Revenue by Type (2021-2032)
- 10.1.2 China Inhaled Nitric Oxide Sales by Type (2021-2032)
- 10.1.3 China Inhaled Nitric Oxide Price by Type (2021-2032)
- 10.2 China Inhaled Nitric Oxide Market Size by Application
- 10.2.1 China Inhaled Nitric Oxide Revenue by Application (2021-2032)
- 10.2.2 China Inhaled Nitric Oxide Sales by Application (2021-2032)
- 10.2.3 China Inhaled Nitric Oxide Price by Application (2021-2032)
11 Asia (Excluding China)
- 11.1 Asia Inhaled Nitric Oxide Market Size by Type
- 11.1.1 Asia Inhaled Nitric Oxide Revenue by Type (2021-2032)
- 11.1.2 Asia Inhaled Nitric Oxide Sales by Type (2021-2032)
- 11.1.3 Asia Inhaled Nitric Oxide Price by Type (2021-2032)
- 11.2 Asia Inhaled Nitric Oxide Market Size by Application
- 11.2.1 Asia Inhaled Nitric Oxide Revenue by Application (2021-2032)
- 11.2.2 Asia Inhaled Nitric Oxide Sales by Application (2021-2032)
- 11.2.3 Asia Inhaled Nitric Oxide Price by Application (2021-2032)
- 11.3 Asia Inhaled Nitric Oxide Market Size by Country
- 11.3.1 Asia Inhaled Nitric Oxide Revenue Grow Rate by Country (2021 VS 2025 VS 2032)
- 11.3.2 Asia Inhaled Nitric Oxide Sales by Country (2021 VS 2025 VS 2032)
- 11.3.3 Asia Inhaled Nitric Oxide Price by Country (2021-2032)
- 11.3.4 Japan
- 11.3.5 South Korea
- 11.3.6 India
- 11.3.7 Australia
- 11.3.8 Taiwan
- 11.3.9 Southeast Asia
12 South America, Middle East and Africa
- 12.1 SAMEA Inhaled Nitric Oxide Market Size by Type
- 12.1.1 SAMEA Inhaled Nitric Oxide Revenue by Type (2021-2032)
- 12.1.2 SAMEA Inhaled Nitric Oxide Sales by Type (2021-2032)
- 12.1.3 SAMEA Inhaled Nitric Oxide Price by Type (2021-2032)
- 12.2 SAMEA Inhaled Nitric Oxide Market Size by Application
- 12.2.1 SAMEA Inhaled Nitric Oxide Revenue by Application (2021-2032)
- 12.2.2 SAMEA Inhaled Nitric Oxide Sales by Application (2021-2032)
- 12.2.3 SAMEA Inhaled Nitric Oxide Price by Application (2021-2032)
- 12.3 SAMEA Inhaled Nitric Oxide Market Size by Country
- 12.3.1 SAMEA Inhaled Nitric Oxide Revenue Grow Rate by Country (2021 VS 2025 VS 2032)
- 12.3.2 SAMEA Inhaled Nitric Oxide Sales by Country (2021 VS 2025 VS 2032)
- 12.3.3 SAMEA Inhaled Nitric Oxide Price by Country (2021-2032)
- 12.3.4 Brazil
- 12.3.5 Argentina
- 12.3.6 Chile
- 12.3.7 Colombia
- 12.3.8 Peru
- 12.3.9 Saudi Arabia
- 12.3.10 Israel
- 12.3.11 UAE
- 12.3.12 Turkey
- 12.3.13 Iran
- 12.3.14 Egypt
13 Value Chain and Sales Channels Analysis
- 13.1 Inhaled Nitric Oxide Value Chain Analysis
- 13.1.1 Inhaled Nitric Oxide Key Raw Materials
- 13.1.2 Raw Materials Key Suppliers
- 13.1.3 Manufacturing Cost Structure
- 13.1.4 Inhaled Nitric Oxide Production Mode & Process
- 13.2 Inhaled Nitric Oxide Sales Channels Analysis
- 13.2.1 Direct Comparison with Distribution Share
- 13.2.2 Inhaled Nitric Oxide Distributors
- 13.2.3 Inhaled Nitric Oxide Customers
14 Concluding Insights
15 Appendix
- 15.1 Reasons for Doing This Study
- 15.2 Research Methodology
- 15.3 Research Process
- 15.4 Authors List of This Report
- 15.5 Data Source
- 15.5.1 Secondary Sources
- 15.5.2 Primary Sources
- 15.6 Disclaimer
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